0x0E Bitsraised in a barn by hippy wolves

Sun Aug 02 09:35:00 CDT 2009

Dr. Suehs pointed me to this article:

Citation: T.L. Lassiter, et al., Neonatal exposure to parathion alters lipid metabolism in adulthood: Interactions with dietary fat intake and implications for neurodevelopmental de•Â?cits, BrainRes. Bull. (2009), doi:10.1016/j.brainresbull.2009.07.002

Exposed baby rat pups to parathion and later in life measured TNF-alpha and TBARS. Later the metabolic and neurological effects partially responded to a high-fat diet. Here is part of the abstract just to tease the article. The full abstract and article are copyrighted by the journal publisher Elsevier (who did the fake science journals pushing products, so this whole thing is tainted and needs to be confirmed by peer replication).

We determined whether neonatal parathion exposure in rats has long-term effects on regulation of adipokines and lipidperoxidation. We also assessed the interaction of these effects with increased fat intake. Rats were given parathion on postnatal days1‰ÛÒ4 using doses (0.1or0.2mg/kg/day) that straddle the threshold for barely detectable cholinesterase inhibition and the •Â?rst signs of systemic toxicity. In adulthood, animals were either maintained on standard chow or switched to a high-fat diet for7 weeks. We assessed serum leptin and adiponectin, tumor necrosis factor in adipose tissues, and thiobarbituricacid reactives pecies (TBARS) in peripheral tissues and brain regions.